Increasing maternal body mass index shows a moderate to strong dose-response relationship with increasing risks of fetal death, stillbirth, neonatal death, perinatal death, and infant death, according to a report published online April 15 in JAMA.

 In what they described as the first meta-analysis to comprehensively summarize the findings regarding maternal overweight and obesity on the one hand and infant mortality risks on the other, researchers compiled data from 38 cohort studies that tallied at least three categories of maternal BMI as well as several separate infant mortality outcomes. Most of the studies were performed in Europe (19) and North America (6), but there also were 6 from Australia, 4 from Asia, 2 from Latin America, and 1 from Africa.

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